In the glycine conjugation pathway, benzoic acid is converted to which compound?

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Multiple Choice

In the glycine conjugation pathway, benzoic acid is converted to which compound?

Explanation:
The main idea is that benzoic acid is detoxified by attaching glycine to it to form a more water‑soluble compound that can be excreted in urine. In this pathway, benzoic acid is first activated to benzoyl-CoA by a CoA ligase using ATP. Then glycine is conjugated to the benzoyl group via glycine N‑acyltransferase, producing hippuric acid (benzoyl glycine). This shift to hippuric acid facilitates excretion and helps eliminate the benzoic acid from the body. The other options aren’t products of this detoxification route: benzoic acid is the substrate, while noradrenaline and dithiocarbamic acid are unrelated to this glycine conjugation process.

The main idea is that benzoic acid is detoxified by attaching glycine to it to form a more water‑soluble compound that can be excreted in urine. In this pathway, benzoic acid is first activated to benzoyl-CoA by a CoA ligase using ATP. Then glycine is conjugated to the benzoyl group via glycine N‑acyltransferase, producing hippuric acid (benzoyl glycine). This shift to hippuric acid facilitates excretion and helps eliminate the benzoic acid from the body. The other options aren’t products of this detoxification route: benzoic acid is the substrate, while noradrenaline and dithiocarbamic acid are unrelated to this glycine conjugation process.

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